Publications

(2024) Acyl-coa synthetase 6 controls rod photoreceptor function and survival by shaping the phospholipid composition of retinal membranes

Wang, Y, S Becker, S Finkelstein, FM Dyka, H Liu, M Eminhizer, Y Hao, RS Brush, WJ Spencer, VY Arshavsky, JD Ash, J Du, MP Agbaga, F Vinberg, JM Ellis, and ES Lobanova

Communications Biology

(2024) Contribution of intraflagellar transport to compartmentalization and maintenance of the photoreceptor cell

Lewis, TR, CM Castillo, NV Klementieva, Y Hsu, Y Hao, WJ Spencer, AV Drack, GJ Pazour, and VY Arshavsky

PNAS

(2023) The wave complex drives the morphogenesis of the photoreceptor outer segment cilium

Spencer, WJ, NF Schneider, TR Lewis, CM Castillo, NP Skiba, and VY Arshavsky

PNAS

(2023) Absolute quantification of photoreceptor outer segment proteins

Skiba, NP, TR Lewis, WJ Spencer, CM Castillo, A Shevchenko, and VY Arshavsky

Journal of Proteome Research

(2023) A ciliary branched actin network drives photoreceptor disc morphogenesis

Spencer, WJ and VY Arshavsky

Advances in Experimental Medicine and Biology

(2023) Extracellular vesicles highlight many cases of photoreceptor degeneration

Spencer, WJ

Frontiers in Molecular Neuroscience

(2021) Tmem67, tmem237, and embigin in complex with monocarboxylate transporter mct1 are unique components of the photoreceptor outer segment plasma membrane

Skiba, NP, MA Cady, L Molday, JYS Han, TR Lewis, WJ Spencer, WJ Thompson, S Hiles, NJ Philp, RS Molday, and VY Arshavsky

Molecular and Cellular Proteomics

(2020) Photoreceptor discs: Built like ectosomes

Spencer, WJ, TR Lewis, JN Pearring, and VY Arshavsky

Trends in Cell Biology

(2020) Comprehensive identification of mRNA isoforms reveals the diversity of neural cell-surface molecules with roles in retinal development and disease

Ray, TA, K Cochran, C Kozlowski, J Wang, G Alexander, MA Cady, WJ Spencer, PA Ruzycki, BS Clark, A Laeremans, MX He, X Wang, E Park, Y Hao, A Iannaccone, G Hu, O Fedrigo, NP Skiba, VY Arshavsky, and JN Kay

Nature Communications

(2019) PRCD is essential for high-fidelity photoreceptor disc formation

Spencer, WJ, JD Ding, TR Lewis, C Yu, S Phan, JN Pearring, KY Kim, A Thor, R Mathew, J Kalnitsky, Y Hao, AM Travis, SK Biswas, WK Lo, JC Besharse, MH Ellisman, DR Saban, ME Burns, and VY Arshavsky

PNAS

(2019) Photoreceptor disc membranes are formed through an arp2/3-dependent lamellipodium-like mechanism

Spencer, WJ, TR Lewis, S Phan, MA Cady, EO Serebrovskaya, NF Schneider, KY Kim, LA Cameron, NP Skiba, MH Ellisman, and VY Arshavsky

PNAS

(2019) PRCD is a small disc-specific rhodopsin-binding protein of unknown function

Spencer, WJ and VY Arshavsky

Advances in Experimental Medicine and Biology

(2018) Transducin beta-subunit can interact with multiple g-protein gamma-subunits to enable light detection by rod photoreceptors

Dexter, PM, ES Lobanova, S Finkelstein, WJ Spencer, NP Skiba, and VY Arshavsky

eNeuro

(2017) Photoreceptor discs form through peripherin-dependent suppression of ciliary ectosome release

Salinas, RY, JN Pearring, JD Ding, WJ Spencer, Y Hao, and VY Arshavsky